Biotech
Drug developers with approved medicines, built mainly on biologic and genetic science.
Grouped with the help of an AI model and reviewed by our editors. The line under each company says why it is here.
Share prices are the Nov 11, 2026 close, from the IEX exchange feed.
Grade mix
A 8B 4C 5D 1F 1
Revenue growing
18 of 19
Free cash flow growing
13 of 18
Median price move, 1 year
+29.0%
- VRTXVERTEX PHARMACEUTICALS INC / MA
BiotechnologyMarket cap $138.7BP/E 35.22
$547.02+26.0%1YSince added +12.7%
B+- Growth & cash
- Growing strongly
- Business trend
- Steady
- Business quality
- Strong
- Getting better
- Improving
Revenue
$13B+10.5%Profit
$4B+8.2%Free cash flow
$3.2B-4.0%Why it is here: Develops and sells cystic fibrosis and other medicines
- REGNREGENERON PHARMACEUTICALS, INC.
BiotechnologyMarket cap $101.3BP/E 21.18
$959.45+41.5%1YSince added +27.4%
C+- Growth & cash
- Growing
- Business trend
- Accelerating
- Business quality
- Strong
- Getting better
- Improving
Revenue
$16.9B+18.6%Profit
$4.8B+5.2%Free cash flow
$3.8B-9.4%Why it is here: Develops and sells antibody therapies for eye, allergy and cancer conditions
- GILDGILEAD SCIENCES, INC.
Drug manufacturers generalMarket cap $210.5BNo P/E (operating loss)
$169.73+40.9%1YSince added +14.8%
A- Growth & cash
- Growing strongly
- Business trend
- Steady
- Business quality
- Mixed
- Getting better
- Improving
Revenue
$31B+6.5%Profit
-$3.9B-147.6%Free cash flow
$13.8B+50.4%Why it is here: Sells medicines for HIV, liver disease and cancer
- ALNYALNYLAM PHARMACEUTICALS, INC.
BiotechnologyMarket cap $21.4BP/E 68.58
$159.80-64.7%1YSince added -28.6%
B+- Growth & cash
- Growing strongly
- Business trend
- Slowing
- Business quality
- Strong
- Getting better
- Improving
Revenue
$3.7B+65.2%Profit
$2.6B+2,136.9%Free cash flow
$465.4M+1,192.7%Why it is here: Develops and sells RNAi therapeutics
- BIIBBIOGEN INC.
Drug manufacturers generalMarket cap $37.5BP/E 109.22
$253.39+56.9%1YSince added +10.7%
A- Growth & cash
- Growing strongly
- Business trend
- Steady
- Business quality
- Solid
- Getting better
- Mixed
Revenue
$10.3B+2.3%Profit
$347.5M-78.4%Free cash flow
$2.1B-10.1%Why it is here: Develops and sells therapies for neurological diseases
- INSMINSMED INC
BiotechnologyMarket cap $26.5BNo P/E (operating loss)
$120.64-37.9%1YSince added +24.7%
C-- Growth & cash
- Growing
- Business trend
- Steady
- Business quality
- Weak
- Getting better
- Mixed
Revenue
$1.5B+240.0%Profit
-$605.6M+48.8%Free cash flow
-$627.6M+30.7%Why it is here: Develops and sells therapies for rare lung diseases
- UTHRUnited Therapeutics Corporation
Drug manufacturers specialty and genericMarket cap $25.4BP/E 22.48
$595.58+29.0%1YSince added +9.6%
C+- Growth & cash
- Growing strongly
- Business trend
- Slowing
- Business quality
- Strong
- Getting better
- Improving strongly
Revenue
$3.2B+1.9%Profit
$1.2B-3.2%Free cash flow
$867.2M-22.7%Why it is here: Sells therapies for pulmonary arterial hypertension
- NBIXNEUROCRINE BIOSCIENCES, INC.
Drug manufacturers specialty and genericMarket cap $17.6BP/E 25.87
$174.35+18.7%1YSince added +29.0%
A+- Growth & cash
- Growing strongly
- Business trend
- Accelerating
- Business quality
- Strong
- Getting better
- Improving
Revenue
$3.7B+38.0%Profit
$702.5M+64.1%Free cash flow
$1B+75.3%Why it is here: Develops and sells therapies for neurological and endocrine disorders
- MRNAModerna, Inc.
BiotechnologyMarket cap $100.6BNo P/E (operating loss)
$248.70+831.1%1YSince added +15.0%
C-- Growth & cash
- Growing
- Business trend
- Accelerating
- Business quality
- Weak
- Getting better
- Deteriorating
Revenue
$2.5B+13.1%Profit
-$2.8B+10.5%Free cash flow
-$2B+25.7%Why it is here: Develops mRNA vaccines and therapies
- BMRNBioMarin Pharmaceutical Inc
BiotechnologyMarket cap $11.3BNo P/E
$58.32+5.4%1YSince added +7.3%
B- Growth & cash
- Growing strongly
- Business trend
- Steady
- Business quality
- Mixed
- Getting better
- Improving
Revenue
$3.7B+18.1%Profit
-$19.1M-103.7%Free cash flow
$557.9M-33.0%Why it is here: Develops and sells therapies for rare genetic diseases
- INCYINCYTE CORPORATION
BiotechnologyMarket cap $24.9BP/E 65.01
$122.23+12.9%1YSince added +12.6%
C- Earnings & book value
- Growing
- Business quality
- Mixed
- Getting better
- Improving strongly
Revenue
$6B+24.9%Profit
$403.4M-66.1%Free cash flow
$892.1MNo comparable yearWhy it is here: Develops and sells oncology and inflammation therapies
- EXELEXELIXIS, INC.
BiotechnologyMarket cap $17.3BP/E 21.17
$70.71+62.2%1YSince added +18.8%
A+- Growth & cash
- Growing strongly
- Business trend
- Steady
- Business quality
- Strong
- Getting better
- Improving
Revenue
$2.5B+9.1%Profit
$885.1M+30.6%Free cash flow
$1.2B+48.9%Why it is here: Develops and sells cancer therapies
- BNTXBioNTech SE
BiotechnologyMarket cap $22BNo P/E (operating loss)
$87.64-21.5%1YSince added -1.5%
F- Growth & cash
- Mixed
- Business trend
- Contracting
- Business quality
- Mixed
- Getting better
- Improving
Revenue
$2.7B-23.2%Profit
-$1.6B-157.7%Free cash flow
$314M+456.5%Why it is here: Develops mRNA vaccines and cancer therapies
- JAZZJazz Pharmaceuticals plc
BiotechnologyMarket cap $15.9BP/E 80.84
$248.18+81.5%1YSince added +18.0%
A- Growth & cash
- Growing strongly
- Business trend
- Steady
- Business quality
- Mixed
- Getting better
- Improving
Revenue
$4.7B+13.5%Profit
$206M+155.9%Free cash flow
$1.6B+21.3%Why it is here: Develops and sells neuroscience and oncology therapies
- HALOHALOZYME THERAPEUTICS, INC.
BiotechnologyMarket cap $11.6BP/E 25.36
$101.69+44.0%1YSince added -7.2%
A+- Growth & cash
- Growing strongly
- Business trend
- Steady
- Business quality
- Strong
- Getting better
- Improving
Revenue
$1.8B+45.0%Profit
$485.4M-18.5%Free cash flow
$885.9M+47.1%Why it is here: Licenses drug delivery technology and sells enzyme-based therapies
- ASNDAscendis Pharma A/S
BiotechnologyMarket cap $16.1BNo P/E (operating loss)
$259.10+30.1%1YSince added +16.0%
D- Earnings & book value
- Mixed
- Business quality
- Mixed
- Getting better
- Improving
Revenue
$1.2B+113.4%Profit
-$254.8M+39.7%Free cash flow
-$293.2M+54.2%Why it is here: Develops and sells endocrinology rare disease therapies
- BBIOBridgeBio Pharma, Inc.
BiotechnologyMarket cap $15.5BNo P/E (operating loss)
$79.53+20.1%1YSince added +25.6%
B- Growth & cash
- Growing strongly
- Business trend
- Steady
- Business quality
- Mixed
- Getting better
- Deteriorating
Revenue
$945.5M+167.3%Profit
-$573.8M+28.6%Free cash flow
-$369.8M+36.9%Why it is here: Develops therapies for genetic diseases
- CORTCORCEPT THERAPEUTICS INC
BiotechnologyMarket cap $8.2BP/E 58.68
$74.52-4.9%1YSince added -36.7%
A+- Growth & cash
- Growing strongly
- Business trend
- Accelerating
- Business quality
- Strong
- Getting better
- Mixed
Revenue
$963.6M+30.0%Profit
$162.3M+52.9%Free cash flow
$194.6M+19.2%Why it is here: Develops and sells cortisol-modulating therapies
- KRYSKrystal Biotech, Inc.
BiotechnologyMarket cap $9.2BP/E 41.90
$308.82+52.1%1YSince added -3.9%
A+- Growth & cash
- Growing strongly
- Business trend
- Steady
- Business quality
- Strong
- Getting better
- Improving
Revenue
$470M+26.0%Profit
$225.2M+13.2%Free cash flow
$310.1M+87.3%Why it is here: Develops and sells topical gene therapies for rare diseases
Green and red compare each figure with the same window a year earlier. Grades and checks are the company page's own; nothing here is a recommendation.
Lists are their owners' own, and notes and comments are opinions. Grades describe businesses from their filings; nothing here is a recommendation to buy or sell.
DiscussionNo comments yet
Be civil and stick to the companies. Comments are opinions, not advice.